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Despite having these natural antioxidant defenses, spermatozoa are highly susceptible to oxidative stress due to several inherent limitations in their ability to counteract excessive ROS

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This translational gap can be attributed to interspecies differences, the complexity and heterogeneity of disease models, and the limited ability of current models to fully reproduce the multifactorial nature of BIPN in patients with multiple myeloma

This approach takes longer to reach full therapeutic doses but can be particularly valuable for people who had severe reactions to GLP-1 medications at standard starting doses