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On April 13, 2022, the relevant tests suggested severe anemia (HGB 57 g/L) with serum iron of 28.5 mol/L and reticulocyte of 0.05%

Further pharmacological and genetic evidence has confirmed the contribution of H 2 -stimulated brassinosteroids (Wang et al., 2022) and glutathione (Zhang et al., 2022) in the above responses

Depending on the extreme extent of the enzyme and pH changes, these changes may permanently "destroy" the enzyme, or once the conditions return to the desired range of the enzyme, the enzyme will return to normal

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