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And some of the labeling, especially the axes and legend, appears to be low resolution

While metabolomics focuses on identifying and quantifying the metabolites, fluxomics has emerged as the process of studying metabolic fluxes, or the rates of biochemical reactions, in a biological system, which is a more dynamic and quantitative approach to understanding metabolism (Emwas et al., 2022)

Immunosuppressive agents with intrinsic antifungal activity are emerging as candidates for drug repurposing, including calcineurin inhibitors (e.g., cyclosporine, pimecrolimus, tacrolimus/FK506), mTOR inhibitors (e.g., rapamycin), antimetabolites (e.g., mizoribine [MZP], mycophenolic acid [MPA]), and glucocorticoids