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B vitamins are often depleted in individuals with substance abuse, particularly alcohol abuse, due to poor nutritional intake, increased demand for metabolizing substances and poor gastrointestinal absorption

For the anaerobic life forms that inhabited the anoxic and sulfidic atmosphere of early Earth, antioxidants provided an evolutionary advantage by protecting against localised or trace oxygen levels 1,9,10

Other recent reports involving SOD knock-outs have revealed that Mn- SOD is essential for life whereas Cu/Zn-SOD is not

Since this study showed that human lymphocytes cultured in the presence of DA suffered less radiation-induced damage, DA is a potential candidate for pretreatment before ionizing radiation exposure