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An ideal antibody for gluten analysis should be not only a reliable indicator of the presence of prolamins from cereal species known to be toxic to CD patients but also should recognize the specific intramolecular regions responsible for such immunotoxicity [1]

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However, for squamous epithelia and urothelium, the spheroidal structure of organoids is quite different from the continuous sheet of the tissue, and differentiated cells are not shed but accumulate in the center of the organoid 23,24,25,26 (Fig

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