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Lung cadmium content was determined by inductively coupled plasma-mass spectrometry (ICP-MS) analysis, and TOPO-PMAT QD disposition was modeled using PKSolver as described in Methods

Effects on cognition and global function were evaluated with the Alzheimers Disease Assessment Scale Cognitive Subscale (ADAS-Cog) and the Clinician Interview-Based Impression of Change with Caregiver Input scale (CIBIC+) at 4, 12, and 24 weeks after the start of injections

The treatment arm achieved an 18 percent mean reduction in visceral adipose tissue versus a small increase in placebo, with statistically significant improvements in triglycerides (minus 50 mg/dL), total cholesterol, and patient-reported body image

CCS Chemistry 0 , 1-14 Wang, S.-Z