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Clin Chim Acta 2009

A vitamin B12 deficiency, however, is not considered a sign of cancer

These include chromatographic separation methods and mass spectrometric analysis to confirm peptide identity, molecular integrity, and purity specifications

Perhaps 12 persons per million per year are diagnosed with this disease, but many investigators feel that the frequency is greater, as it is often mis-diagnosed as Raynaud's disease, a condition that involves capillary congestion and swelling especially of the extremities