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doi: 10.1101/cshperspect.a026104 10 ChoH

The activity of key enzymes in the sulfur assimilation pathway is also regulated by feedback inhibition from downstream products, similar to the regulation seen in plants

If these four areas have been addressed and the patient is genuinely stalled at an appropriate dose, with adequate protein, with strength training in place, and with honest tracking confirming the deficit, then the conversation about adjunct therapy becomes meaningful