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Flavonoids possess remarkable antioxidant capacity and can reduce or inhibit oxidative stress caused by free radicals through multiple mechanisms, including direct scavenging of reactive oxygen species (ROS), activation of antioxidant enzymes, and inhibition of oxidative enzymes that generate ROS (Williamson et al

4-MESC markedly reduced LPS-induced elevated levels of ROS and lipid peroxidation (malondialdehyde levels) and enhanced the superoxide dismutase (SOD) activity and glutathione levels, which revealed its anti-oxidant potential against oxidative stress

Depending on dose and duration, PCBs can disrupt the production and disposition of thyroid hormones at a variety of levels and thereby may potentially interact with iodine in impairing the thyroid gland

& Rafiquzzaman, M