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10.1016/j.neuropharm.2005.10.012 49 HuangZ.PanX.ZhouJ.LeungW

Using these enzyme preparations with a defined GSH concentration (20 M) in the established two-step in vitro reactions, we found that the extent of conversion of the ultrafiltered flavan-3,3,4-triol ( 4 ) depended on the applied concentration of the purified Pt GSTF8, confirming that this enzyme is required and sufficient for the observed conversion to cyanidin (Extended Data Fig

however, in PD patients, it becomes persistent and leads to the accumulation of activated myofibroblasts that alters the healthy structure and function of the peritoneal membrane, thus hindering the effective treatment (Strippoli et al., 2020