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Varone E, Chernorudskiy A, Cherubini A, Cattaneo A, Bachi A, Fumagalli S, et al

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Activating sirtuins through adequate NAD+ levels is associated with improved mitochondrial function, reduced inflammation, and extended cellular lifespan

GAD patients demonstrated broader SCFA depletion, with decreased levels of Faecalibacterium, Eubacterium rectale, Butyricicoccus , and Lachnospira , bacteria integral to maintaining mucosal homeostasis and modulating host-microbiota immune interactions