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doi: 10.1146/annurev.genom.6.080604.162324 41 Genetic Analysis of Psoriasis Consortium & the Wellcome Trust Case Control Consortium

US is routinely used to diagnose lesions

However, it has been shown that the CHAC1 protein, found in higher eukaryotes, has -glutamylcyclotransferase activity and also specifically degrades intracellular glutathione