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For instance, butyrate enhances astrocytic neurotrophic support, promoting slow-wave sleep and cognitive function [113,114,115,116]

The activities of superoxide dismutase (SOD) and glutathione peroxidase (GPx) constitute a first-line antioxidant defense system that plays a key and fundamental role in the total defense mechanisms and strategies in biological systems 81

Other Therapies Modulating NRF2 In addition to the previously discussed classes of drugs, many other compounds have shown important biological activity via Nrf2