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Description

Continuous administration without washout can lead to adaptive downregulationwhere receptors become less responsive to MOTS-c signaling or NNMT inhibition becomes less effective due to compensatory upregulation

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doi: 10.3168/jds.2015-10157 93 OsorioJ

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Mechanisms of Central Auditory Damage The mechanisms that contribute to central auditory deficits associated with noise damage and aging have received much less attention than those underlying cochlear damage

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Completing this in advance allows for a more thorough and personalised assessment, ensuring that any TRT recommendations are made in the context of your full clinical picture

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