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10.1073/pnas.1603244113 Proc

Authors contribution Cravin G: Writing-original draft, writing-review & editing

This work develops the first mathematical model for the GSH antioxidant system in the outer retina, capturing the most essential components for formation of ROS, GSH production, its oxidation in detoxifying ROS, and subsequent reduction by NADPH

Their intricate roles extend far beyond the basics of metabolic regulation and hold the potential to unlock novel insights into the complex etiology and progression of various neurological disorders, including depression, Alzheimers disease, and epilepsy