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5.1.12 Niacinamide Niacinamide, also known as vitamin B3, is the active form of niacin (Rolfe, 2014) and can be used in melasma (Navarrete-Sols et al., 2011) and hyperpigmentation (Kimball et al., 2010) disorders through the regulation of melanosomes transfer from the melanocytes to the keratinocytes

A separate 2024 study reached a similar conclusion and credited the hydrating benefits to its film-forming properties

5.2 Selenium compounds Selenium compounds include inorganic selenium compounds and organic selenium compounds, with the main organic forms being selenomethionine and selenocysteine, and the inorganic forms being selenite, selenide, selenate, and selenium, which are integral to various biological functions ( Figure 5 ) (209)

This dosing regimen produced measurable senescent cell clearance and functional improvements including enhanced physical activity, improved kidney function markers, and restored fur quality