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Bilirubin is antioxidant of possible physiological importance

Gen Pharmacol 22(2):393397 Liu Y, Li J, Zhu HJ (2024) Regulation of carboxylesterases and its impact on pharmacokinetics and pharmacodynamics: an up-to-date review

Oxidative stress arises from an imbalance between the production of ROS and the bodys antioxidant defenses

Similarly, the PD-specific pattern (PDSP) in an adeno-associated viral vector (AAV)-based -synuclein (-syn) rat model of PD indicated that except entorhinal, insular and ipsilateral somatosensory cortex, all cortical regions, as well as striatum, midbrain, pons and medulla oblongata, have metabolic hyperfunction, while thalamus, hippocampus and cerebellum have metabolic hypofunction