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although there have been some instances of its administration in trials involving patients,safety and effectiveness in this population are not firmly established.Pediatric dosages should be used cautiously, determined based upon each child's clinical situation

Although much of the current research focuses on the role of RvD1 and AT-RvD1 in salivary gland inflammation, other SPMs with similar pro-resolving and anti-inflammatory properties should also be explored for their potential to alleviate SS disease progression