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Earlier this month, Swiss pharmaceutical giant Roche struck a deal worth up to $5.3 billion to develop Danish biotech Zealand Pharma's amylin analog obesity drug candidate

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In the OSB, 4HBA/MVA and HGA/MVA pathways, chorismate, the product of the shikimate pathway, 23 ultimately provides one of the rings in the core 1,4-naphthalenoid structure, although the chorismate product from which each pathway starts is different (Figure 2)