foxo4-dri senolytic 2023 2024 induces keloid senescent fibroblast apoptosis by promoting nuclear exclusion of upregulated p53-serine 15 phosphorylation The disordered p53 transactivation domain
The disordered p53 transactivation domain is the target of FOXO4 and the senolytic compound FOXO4 DRI Nature Communications FOXO4 DRI part 1 #peptide #molecule #research #health #information CHK2 USP37 axis stabilizes FOXO4 to sustain senescence and evade apoptosis PNAS Senolytic Peptide FOXO4 DRI Selectively Removes Senescent Cells From in vitro Expanded Human Chondrocytes PMC
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