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Gene ontology (GO) classification analysis revealed that differentially expressed genes were predominantly associated with immune system processes, responses to stimuli, and metabolic regulation at the biological process level, while intracellular and protein-containing complexes were enriched at the cellular component level, and binding- and catalytic-related functions were dominant at the molecular function level (Fig

In the absence of a breakthrough in treatment the number of AD patients is predicted to reach 16 million in the U.S

GLS is an enzyme that converts glutamine to glutamate, and small molecule inhibitors targeting GLS include CB-839, 968 and BPTES

10.1002/jev2.12134 116 SidhomK.ObiP