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HOXB4 is another HOX gene family member which appears to have both tumor suppressive and oncogenic potential depending on the cancer type

Conclusions Collectively, these findings suggest that Schwann-like cells converted from GMSCs represent a promising source of supportive cells for regenerative therapy of PNI through their dual functions, neurotrophic effects, and immunomodulation of pro-inflammatory (M1)/pro-regenerative (M2) macrophages