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C.et al (1998)

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1 H-NMR (400 MHz, CDCl 3 ) ppm = 7.72 (dd, J = 0.6 Hz, J = 8.2 Hz, 1H, Ar-H), 7.66 (dd, J = 0.8 Hz, J = 1.8 Hz, 1H, Ar-H), 7.63 (dd, J = 0.6 Hz, J = 1.5 Hz, 1H, Ar-H), 7.40 (dd, J = 1.5 Hz, J = 8.2 Hz, 1H, Ar-H), 7.28 (dd, J = 0.8 Hz, J = 3.5 Hz, 1H, Ar-H), 6.60 (dd, J = 1.8 Hz, J = 3.5 Hz, 1H, Ar-H), 3.11 (bs, 3 H, -CH 3 ), 3.00 (bs, 3 H, -CH 3 )

Titrate very slowly, especially if the patient has not been on methadone before