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The promise is real, but clinical readiness is not: Preclinical and early human data are compelling, but without large-scale trials, validated delivery methods, and long-term safety data, Epitalon remains an experimental peptide, one to watch closely, but not yet ready for mainstream clinical adoption

XKR8-deficient mice exhibit compromised NET formation and impaired control of Candida albicans pulmonary infection, showing that XKR8 is indispensable for neutrophil-driven immune responses in vivo

Contrary to the satisfactory results of experimental exosome therapy studies, exosomal therapy methods and safety are not entirely clarified (258)

Ye, M., Huang, T., Ni, C., Yang, P