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This infiltration can exacerbate neuroinflammation and disturb the delicate balance of neurotransmitters such as serotonin and dopamine [175,176]

Pairwise comparisons between the stages were performed using the emmeans 68 library in R, with estimated marginal means using Tukey adjustment for multiple comparisons

Accordingly, sex-dependent differences in xenobiotic metabolism are well documented in rats, with greater responses generally seen in males (Mugford and Kedderis, 1998) and with responses influenced by circulating levels of growth hormone (Ahluwalia et al