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Targets for clear cell renal cell carcinoma include the NF-B agonists IB kinase b and caspase recruitment domain protein 9 (CARD9), MAPK1, fibronectin, collagen IV, RpB1 (the large subunit of RNA polymerase II), human antigen R (HuR), and Akt (also known as protein kinase B)[62]

Isoniazid (INH), as an anti-tuberculosis drug, damages the liver and induces lipid peroxidation leading to apoptosis of liver cells through glutathione depletion (175)

FFortunately, experimental autoimmune uveitis (EAU) in Lewis rats serves as an animal model closely resembling autoimmune uveitis in humans and other animals

Overall, chemotherapy drugs commonly utilized in clinic have been shown to induce not only apoptosis, but additionally ferroptosis and autophagy