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Nat Nanotechnol, 2016, 11: 97785

Further improvements on selectivity and efficiency, may be achieved by investigating nanoparticles that respond to multiple stimuli and bear multiple functionalities

IGF-1 is a critical mediator of muscle hypertrophy through activation of mTOR signaling and enhanced protein synthesis. Glass, Nature Reviews Molecular Cell Biology In essence: HGH = upstream signal that initiates the process IGF-1 = downstream executor that builds and repairs tissue Benefits Comparison: IGF-1 vs HGH While HGH and IGF-1 both promote growth, recovery, and performance, they do so through different pathways and timelines

I cant seem to find much information on the temperature side-effect