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However, it can be combined with the oral iron chelator deferiprone (DFP) to achieve enhanced removal of cardiac iron, based on a shuttle effect that employs the superior capacity of DFP to mobilize cardiac iron, 35 which is then transferred to DFO for excretion

Indole-3-propionic acid is a potent hydroxyl radical scavenger produced exclusively by the commensal gut bacteria Clostridium sporogenes 66 and normally found in the plasma and cerebrospinal fluid

In a rat model of cerebral ischemia-reperfusion induced by bilateral common carotid artery occlusion using the modified Pulsinelli method, pretreatment with -tocopherol (100 mg/kg, administered subcutaneously for 7 days before ischemia) significantly mitigated brain injury

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