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Methods: By using RNASeq data of CRC patients from The Cancer Genome Atlas (TCGA) database, we divided the patients into normal group(58 patients)and tumor group(446 patients), and analyzed the expression and prognostic value analysis of IGF-1,IGF1R and RAGE

Published research has explored its role in promoting angiogenesis (new blood vessel formation), upregulating VEGF (vascular endothelial growth factor), stimulating fibroblast migration and collagen deposition, modulating nitric oxide pathways, and protecting the gastrointestinal lining

Axonal transport of late endosomes and amphisomes is selectively modulated by local Ca 2+ efflux and disrupted by PSEN1 loss of function