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Carter CJ, Blizard RA

Agouti-related protein as the glucose signaling sensor in the central melanocortin circuits in regulating fish food intake

Another example is systemic lupus erythematosus (SLE), a systemic autoimmune disease characterized by the production of autoantibodies against nuclear antigens

By pre-mixing 'light' labelled samples with 'heavy' labelled standards prior to analysis, any potential matrix effects are compensated for, since each analyte/internal standard pair is similarly affected by the sample matrix