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In addition, an extra boost of choline has been added, which contributes to normal lipid metabolism

More direct evidence indicates that the gut microbiota of Apoe / mice are adjusted, short-chain fatty acids are up-regulated, and the degree of AS is mitigated after 12 weeks of metformin intervention (93)

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4.3 Effect on neuro-developmental Throughout the developmental process, the brain exhibits heightened energy demands for synthesizing fundamental cellular structures, neurotransmitters, nucleic acids, proteins, carbohydrates, and lipids that are indispensable for neuronal growth and myelination ( -oxidationa major energy-yielding pathway