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Mansoor MA, Stea TH, Schneede J, Reine A

Age-related macular degeneration masquerade: a review of pentosan polysulfate maculopathy and implications for clinical practice

It is not intended as a standalone therapeutic dose for severe B12 deficiency, which would require separate supplementation at different intervals and doses under veterinary guidance

However, the development of ex vivo slice culture models has provided an alternative model that bridges the gap between in vitro and in vivo models, enabling the investigation of demyelination and remyelination under controlled conditions, with the added advantage of reduced cost and ethical considerations (Humpel, 2015)