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the fatty-acid modification supports once-weekly dosing

doi: 10.1093/brain/awaa309 105 ZhaoYHuangYCaoYYangJ

For instance, blood vessels provide a route for the arrival of immune cells to the tumor, and through the expression of adhesion molecules (selectins and integrins), and the secretion of chemokines and cytokines, BECs participate in immune cell activation, migration, and recruitment, and play a crucial role during the extravasation of immune cells (89)