is part of the antioxidant glutathione peroxidase Participation in Prevention Cardiovascular Diseases General reaction mechanisms for antioxidant

Belangrijke oorzaken van een verlaagd glutathionniveau zijn: Chronische stress en slaapgebrek: langdurige activatie van het stresssysteem verhoogt oxidatieve stress, waardoor glutathion sneller uitgeput raakt

Chan LS, Liu J, Li M, Li L, Tao Q, Mok TSK

Consequently, gas exchange is obstructed, and edema develops, causing diffuse alveolar damage (DAD) and the formation of a hyaline membrane along the alveolar walls, which is visible radiologically as patchy ground-glass patterns [6]

however, disruption of mitochondrial iron homeostasis enlarges the labile iron pool (LIP), intensifying ROS production through iron-catalyzed reactions