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This study provides an early report of the loss of glial cells within the PFC of patients with mood disorders, consistent with the hypothesized glutamate abnormalities in these disorders

doi: 10.1016/j.lfs.2023.122388 65 EbersoleJLKirakoduSSNguyenLMGonzalezOA

Recent studies have shown that artemether treatment in diabetic mice led to decreased levels of branched-chain amino acids and citrulline, indicating a potential alteration in amino acid metabolism in DKD [115]