ipamorelin clinical trial safety growth hormone secretagogue Selectivity in Secretion: What the Preclinical Record Shows Ipamorelin: The Selective GH Secretagogue

Lloyd-Jones D, Adams RJ, Brown TM, Carnethon M, Dai S, De Simone G, Ferguson TB, Ford E, Furie K, Gillespie C, Go A, Greenlund K, Haase N, Hailpern S, Ho PM, Howard V, Kissela B, Kittner S, Lackland D, Lisabeth L, Marelli A, McDermott MM, Meigs J, Mozaffarian D, Mussolino M, Nichol G, Roger VL, Rosamond W, Sacco R, Sorlie P, Roger VL, Thom T, Wasserthiel-Smoller S, Wong ND, Wylie-Rosett J, American Heart Association Statistics Committee and Stroke Statistics Subcommittee

Literatur Huhn M et al

Mutations as well as aging related modification of -crystallins that affect the structure, oligomerization and chaperone function, lead to decreased solubility and increased protein aggregation, making the lens prone to the development of congenital or senile cataracts (163)

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