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Sonodynamic therapy for gliomas

Investigating on nucleophiles, diverse aromatic rings were cross-linked with amines, mercaptans, and electron-rich aromatics modularly, affording aza-disulfides, trisulfides, and diaryl disulfides, respectively

(d) promoting antioxidant molecules and the expression of related genes involved in mitochondrial energy biogenesis, mainly through AMPK/SIRT1/Nrf2, ERK/p38 Mitogen-activated protein kinase (MAPK), and PTEN/Akt signaling pathways