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For people who wake up ravenous or need to get out the door quickly, that 60-90 minute wait can feel like an eternity

121(11):20742083 Yousefi S, Gold JA, Andina N, Lee JJ, Kelly AM, Kozlowski E, Schmid I, Straumann A, Reichenbach J, Gleich GJ, Simon HU (2008) Catapult-like release of mitochondrial DNA by eosinophils contributes to antibacterial defense

Options include: Topical azole antifungals : Clotrimazole, miconazole, or tioconazole creams or suppositories used for 1-7 days depending on formulation strength Oral fluconazole : A single 150 mg dose for uncomplicated infections, available by prescription Combination therapy : Topical treatments for external symptoms plus oral medication for internal infection Pregnant patients should use topical azole therapy for 7 days and avoid oral fluconazole

In summary, mutations in DNMT3b, ZBTB24, CDCA7, and HELLS disturb the normal process of DNA methylation, which is critical to the pathogenesis of ICF syndrome (90)