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Kim NW, Piatyszek MA, Prowse KR, Harley CB, West MD, Ho PL et al

49 Cumulatively, these findings suggest supplementation with homocysteine-lowering B vitamins may confer benefits even among individuals whose homocysteine does not exceed normal lab reference ranges

Although these data suggest a role for NO in erlotinib resistance, the levels of changes observed as compared with those seen earlier (Figures 2 and 3) suggest that changes in NO are not solely responsible for resistance downstream of decreased GSH levels