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Gao J, Peng D, Zhang X, Hao Z, Zhou J, Fan S, et al

Figure 6 Our observations implied that MAPKAPK2 was associated with reduced KEAP1 levels and enhanced Nrf2 nuclear localization, concomitant with increased HO-1 expression, suggesting a potential role in reinforcing antioxidant defenses in vitiligo melanocytes

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This neuroinflammatory response includes the rapid activation of resident glial cells (microglia and astrocytes), followed by the recruitment of peripheral leukocytes to the perihematomal region [9]