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35 NakadA.BatailleL.HamoirV.SempouxC.HorsmansY

doi: 10.1016/j.clnesp.2017.07.004

Microglia initiate central nervous system innate and adaptive immune responses through multiple TLRs

However, not all xenobiotics (including drugs) are conjugated/inactivated by this pathway ( The mercapturic acid pathway ( Figure 1 ) involves the conjugation of the tripeptide, GSH, to xenobiotics (including drugs) to render them more hydrophilic and facilitate their elimination