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H.AalvinkS.SchaapP

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Our first novel observations were that co-injections of L-NAC and L-NACme appeared to diminish the development of physical dependence to fentanyl on the basis that the NLX-precipitated withdrawal phenomena (e.g., behavioral responses, hypertension and tachycardia) were far less than in rats that received co-injections of fentanyl + vehicle

This disruptor increased SOD-like activity (increasing the concentration of hydrogen peroxide) and suppressed catalase-like activity, enhancing the overall cellular level of hydrogen peroxide and supporting the efficacy of chemodynamic therapy