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Guarner F, Khan AG, Garisch J et al (2012) World gastroenterology organisation global guidelines

Some studies have reported associations between the menstrual cycle and BD, particularly in a subgroup of women with enhanced hormonal sensitivity, who seem to experience menstrual cycle effects on depressive, hypomanic, and manic episodes

Colon sections were scored based on four parameters: epithelial damage (03), crypt damage (03), goblet cell depletion (03), and inflammatory cell infiltration (03), and the average score of each parameter was calculated