melanotic macule palate Immunohistochemical features of multifocal melanoacanthoma in the hard palate: a case report | BMC Research Notes Oral Mucosal Melanosis | IntechOpen

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This is done through white blood cells that produce special proteins called antibodies

For example, Legionella pneumophila secretes the effector SdhA, which maintains mitochondrial integrity and limits mtDNA leakage, helping the bacterium to avoid immune hyperactivation ( Beyond the cGAS-STING and NLRP3 inflammasome pathways, mtDNA also serves as a ligand for endosomal TLR9, which recognizes unmethylated CpG motifs in bacterial and mitochondrial DNA (Tripathi et al., 2023)

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