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This makes the monotherapy regression coefficient less robust than the combination finding Heterogeneity in protocols: The included studies used different needle depths (0.52.5 mm), frequencies (weekly to monthly), devices (dermaroller, dermapen, fractional radiofrequency), and treatment durations, which adds variability to the pooled analysis Primarily male populations: Most included studies focused on male androgenetic alopecia

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In short, despite glycines small size and simple structure, it plays a multitude of critical roles in the most important systems in our body