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The development of resistance often arises from cancer cells directly reprogramming the regulatory architecture of these key pathways through epigenetic mechanisms, thereby restoring or maintaining pro-survival signaling outputs without relying on de novo mutations [1, 4]

With increasing pollution and lifestyle choices that contribute to oxidative stress, many individuals may find their natural levels of glutathione insufficient

Remarkably, more than 60% of the analytes could be detected below the WADAs minimum required performance limit (MRPL) of 2 ng/mL for urine [39]