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Additionally, while drugs like SGLT2 inhibitors and GLP-1 receptor agonists have demonstrated benefits in improving cardiac function and glucose metabolism in patients with DCM (107, 108, 111, 113), their side effects present significant limitations in clinical practice

This is why experts in the field emphasize the importance of looking beyond just the genetic test

It is predominantly localized in mitochondria and functions as a sulfurtransferase that converts 3-mercaptopyruvate, which is produced from cysteine by cysteine aminotransferase (CAT), into pyruvate (Figure 2d) (Nag et al., 2006