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Weight at the start, diet, activity, and dosage are some of the things that affect the outcome

This mechanism plays a vital role in decreasing the aging process at the cellular level and may extend human longevity

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showed that in response to ischemia in mouse brain, astrocytes and endothelial cells up-regulate the expression of the inflammatory chemoattractant stromal cell-derived factor 1 (SDF-1) [210]