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DNA takes tens of thousands of oxidative moments every day, and antioxidants are what counteracts the damage associated with free radicals

For example, SASP profiles from iron-induced senescent endometrial cells in endometriosis may differ from those in fibroblasts undergoing telomere-related senescence

Even if the exact conversion mechanism has not been characterised yet, a limited conversion capacity in Western populations (about 25 %) has been highlighted, as opposed to the greater competence of Asian populations (50 %), estimated through urinary equol excretion (Reference Setchell, Brown and Lydeking-Olsen17)