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First, manipulation of host iron metabolism represents a common strategy employed by pathogens, achieved either through inducing iron overload or through suppressing iron-dependent ferroptosis

To put it in plainer terms, they propose that the high levels of oxidative stress and inability of the immune cells to produce proper amounts of energy could explain everything

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Other silybin derivatives are in development, such as the silybinphosphatidylcholine complex, which has shown some efficacy with treatment of non-fatty liver disease (Ferenci, 2016)